eIF2α phosphorylation is pathognomonic for immunogenic cell death
نویسندگان
چکیده
منابع مشابه
The eIF2α serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress
The HIPPO pathway is an evolutionary conserved regulator of organ size that controls both cell proliferation and death. This pathway has an important role in mediating cell death in response to oxidative stress through the inactivation of Yes-associated protein (YAP) and inhibition of anti-oxidant gene expression. Cells exposed to oxidative stress induce the phosphorylation of the alpha (α) sub...
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Growth factors and transcription factors are well known to regulate pluripotent stem cells, but less is known about translational control in stem cells. Here, we use embryonic stem cells (ESCs) to investigate a connection between ESC growth factors and eIF2α-mediated translational control (eIF2α phosphorylation promotes protein expression from mRNAs with upstream open-reading frames, or uORFs)....
متن کاملCorrigendum: “Combinatorial Strategies for the Induction of Immunogenic Cell Death”
[This corrects the article on p. 187 in vol. 6, PMID: 25964783.].
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2018
ISSN: 1350-9047,1476-5403
DOI: 10.1038/s41418-017-0044-9